Head of the Competence Center for the Treatment of Locally Advanced Rectal Cancer and co-head of the Competence Center for the Treatment of Recurrent Pelvic Tumors. The Center is a part of N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia; it cooperates with leading clinics in Europe, such as Royal Mardsen Hospital (London, United Kingdom), AKH Vienna University Hospital (Vienna, Austria), Champalimaud Foundation (Lisbon, Portugal), Netherlands Cancer Institute (Amsterdam, Netherlands). In this Center, patients can undergo a complete cycle of comprehensive treatment for cancer (including preoperative chemoradiotherapy, surgery, and postoperative therapy). Doctors of this center deals with difficult patients with the involvement of all related specialists. There are regular on-line consultations with foreign specialists to develop individual treatment plans. As a result, many patients undergo radical and sphincter-sparing surgeries.
Head of the Russian division of the International Research on Safety and Efficacy of a combination organ-sparing method for the treatment of colorectal cancer (www.iwwd.org). This method includes radiotherapy and subsequent chemotherapy (according to an original technique) with the assessment of treatment efficacy and tumor removal using transanal endoscopic microsurgery).
Dr. Mamedli provides the full range of surgery for colorectal cancer, including minimally invasive surgery (laparoscopic and transanal endoscopic microsurgery) and extensive multivisceral resections with reconstruction of the organs removed.
Research interests
Benign rectal tumors and early-stage rectal cancer: transanal endoscopic microsurgery. Resectable and locally advanced colorectal cancers: personalization of treatment (combination and comprehensive treatment using chemotherapy and chemoradiotherapy). Laparoscopic surgery. Sphincter-sparing and reconstructive surgery in patients with colorectal cancer.
Education
1990–1996
State Medical University
1996–2000
Fellowship in surgery
2004–2006
Fellowship in surgery, Medical University of Vienna (Austria). Supervisor – Professor B. Teleky (president of the European Federation for Colorectal Cancer (AFR)).
Clinical residency in Oncology, then postgraduate education (PhD student).
2011
Dr. Mamedli defended his thesis (candidate of medical sciences) entitled “Variants of combination therapy for middle and lower rectal cancer”.
2016
He had the theme of his doctoral thesis (doctor of medical sciences) approved: “Personalized treatment for rectal cancer”.
Work experience
2000–2004
Surgeon in the hospital of the Ministry of Health of Saudi Arabia, Riyadh.
2006 – present
Currently works in the Department of Proctology, Research Institute of clinical Oncology, N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Fellowships
2013
Training on minimally invasive surgery (transanal endo-operation), Parc Tauli Hospital, (Barcelona, Spain). Mentor – Professor C. Aracil, European expert in transanal endoscopic microsurgery.
2015
ESCP Fellowship, University Hospital Erlangen (Germany). Mentor – Professor V. Hohenberger, chief oncologist and coloproctologist of Germany.
Research activity
Three patents and 1 certificate of invention, N.N. Blokhin National Medical Research Center of Oncology, more than 120 publications in Russian and international research journals
2013
Poster presentation at the ESSO Congress (Amsterdam) “Impact of neoadjuvant chemoradiotherapy on long-term results and sphincter sparing rate in distal rectal cancer patients”; oral presentation at the IASGO Congress (Bucharest) “First results of randomized trial: short course radiotherapy for low rectal cancer combined with chemotherapy with different fluoropyrimidines”; oral presentation at the EFR Congress (Vienna) “Case of non-operative treatment of low rectal cancer – comparision of approaches” (awarded a gold medal)
2014
Oral presentation at the IASGO Congress (Vienna) “Short-course chemoradiotherapy of rectal cancer: influence of tumor size, nodal status and time interval to surgery to pathologic response”; poster presentation at the EMCCC Congress (Amsterdam) “Comparison of traditional laparoscopic and reverse mesorectumectomy for rectal carcinoma”; oral presentation at the ESSO Congress (Liverpool) “Combined treatment of rectal cancer – a novel approach”; oral presentation at the ESCP Congress (Barcelona) “Multimodal treatment of rectal cancer using short-course neoadjuvant radiotherapy with fluoropyrimidines chemotherapy”
2015
Poster presentation at the EAES Congress (Bucharest) “Transanal endoscopic microsurgery in combined treatment of rectal cancer”
2016
Oral presentation at the EFR Congress (Vienna) “From laparoscopic to trans-anal mesorectal excision – comparision of approaches” (awarded a gold medal)
2017
Training workshop on transanal endoscopic microsurgery
2018
Moscow international festival of endoscopy and surgery: “Live” surgery”, master class on endoscopic surgery for rectal cancer
Membership in professional associations
Board member of the Russian Society for Colorectal Cancer (RSCC), European Association for Emdoscopic Surgery (EAES), European Society of Coloproctology (ESCP), Russian Association of Coloproctologists, Russian Society of Clinical Oncology (RUSSCO), and Russian Association of Oncologists (RAO)
